姓名
个人简介
莫秀梅，91热爆
二级教授，博导，上海纳米生物材料与再生医学工程中心主任。曾为京都大学博士后、新加坡国立大学研究院、亚琛工业技术大学访问教授。从事静电纺纳米纤维用于组织再生的研究达二十多年之久，在纳米纤维用于血管再生、皮肤再生、神经再生、肌腱再生、骨和软骨再生中做出了许多成果，还从事医用水凝胶和3D打印组织工程支架研究，主持和承担国家“十三五”重点研发项目、国家高技术研究发展863计划、国家自然科学基金、上海市科委重大重点等基金、企业技术开发项目等100多项，申请有关专利118项，授权专利40项，主编和参编专著15部，发表SCI文章453篇，总引用量1.2万次，h-index为55, ISI Web of Science显示莫秀梅在静电纺丝领域的研究论文发表世界排名第七。研究成果分别荣获2008年上海市技术发明一等奖，2009年国家科技进步二等奖,2015年上海市自然科学三等奖。入选2019，2020,2021年中国高被引学者、荣获姑苏创业领军人才（2020）、第六届“中国侨界贡献（创新人才）奖”（2016）、烟台“蓝海英才计划”高端创新人才（2015）奖励计划、为上海市教育系统三八红旗手（2014）、上海市巾帼建功标兵（2013）。现担任8个学会的副主任委员及理事，包括中国复合材料学会超细纤维分会副主任委员，中国生物材料学会理事，中国生物医学工程协会生物材料分会理事。作为大会主席召开了2015年第二届国际血管组织工程大会、2019年第六届国际静电纺大会、2020年海峡两岸暨港澳生物材料及组织再生青年科学大会， 2021年中德澳三边国际会议。
研究方向
1. 静电纺纳米纤维用于组织再生，包括在神经、小血管、皮肤、肌腱、骨和软骨上的应用。
2. 快速成型三维支架用于骨和软骨再生。
3. 医用水凝胶的制备及组织修复应用
荣誉及获奖情况
1. 2021年入选爱思唯尔（Elsevier）纺织科学与工程学科中国高被引学者
2. 2020年中国产学研合作创新与促进奖产学研合作创新奖，证号20203127，（中国产学研合作促进会）
2. Liyang Wang, Wei Cheng, Jingjing Zhu, Wenyao Li*, Danyang Li, Xi Yang, Weixin Zhao, Mingjun Ren, Jieji Ren, Xiumei Mo, Qiang Fu, Kaile Zhang**, Electrospun nanoyarn and exosomes of adipose-derived stem cells for urethral regeneration: Evaluations in vitro and in vivo, Colloids and Surfaces B: Biointerfaces 2022, 209, 112218
3. Yujie Chen, Wei Xu, Muhammad Shafiq*, Daiying Song, Xianrui Xie, Zhengchao Yuan, Mohamed EL-Newehy, Hany EL-Hamshary, Yosry Morsi, Yu Liu*, Xiumei Mo*, Chondroitin sulfate cross-linked three-dimensional tailored electrospun scaffolds for cartilage regeneration, Biomaterials Advances 2022, 134 , 112643
4. Xinran Song, Yuxin Jiang, Weixing Zhang, Gomaa Elfawal, Kaili Wang, Di Jiang, Huoyan Hong, Jinglei Wu, Chuanglong He, Xiumei Mo, Hongsheng Wang∗,Transcutaneous tumor vaccination combined with anti-programmed death-1 monoclonal antibody treatment produces a synergistic antitumor effect, Acta Biomaterialia 2022,140 , 247–260
5. Jiaqi Wang, Dandan Zhang, Ying Zhu, Xiumei Mo, Patrick C McHugh*, & Qiang Tong**, Astragalus and human mesenchymal stem cells promote wound healing by mediating immunomodulatory effects through paracrine signaling, Regen.Med 2022, 17(4), 219-232
6. Kaili Wang, Xiaoyun Wang, Di Jiang, Yifei Pei, Zhe Wang, Xiaojun Zhou, Jinglei Wu, Xiumei Mo, Hongsheng Wang*, Delivery of mRNA vaccines and anti-PDL1 siRNA through non-invasive transcutaneous route effectively inhibits tumor growth, Composites Part B 2022, 233 , 109648
7. Dongsheng Li, Tong Wang, Juanjuan Zhao, Jinglei Wu,|Shumin Zhang, Chuanglong He, Meifang Zhu, Mohamed EL-Newehy, Hany EL-Hamshary, Yosry Morsi, Yonglin Gao, Xiumei Mo, Prodrug inspired bi-layered electrospun membranewith properties of enhanced tissue integration for guidedtissue regeneration,J Biomed Mater Res.2022;1–13
8. Chenghao Yu· Tianrui Wang· Hongcui Diao· Na Liu· Yi Zhang· Hongyuan Jiang· Peng Zhao· Zhengyi Shan· Zewen Sun· Tong Wu* · Xiumei Mo· Tengbo Yu*，Photothermal‑Triggered Structural Change of Nanofber Scafold Integrating with Graded Mineralization to Promote Tendon–Bone Healing，Advanced Fiber Materials,
9. Jun Li, Chao Xue, Hao Wang, Shiyan Dong, Zhaogang Yang, Yuting Cao, Binan Zhao, Biao Cheng, Xianrui Xie, Xiumei Mo, Wen Jiang,* Hengfeng Yuan,* and Jianfeng Pan*，Hybrid Nanofibrous Composites with Anisotropic Mechanics and Architecture for Tendon/Ligament Repair and Regeneration，Small2022, 2201147
10. Mingyue Liu, Muhammad Shafiq, Binbin Sun, Jinglei Wu, Wei Wang,Mohamed EL-Newehy, Hany EL-Hamshary, Yosry Morsi, Onaza Ali,Atta ur Rehman Khan, and Xiumei Mo*， Composite Superelastic Aerogel Scaffolds ContainingFlexible SiO2Nanofibers Promote Bone Regeneration，Adv. Healthcare Mater.2022, 2200499
11. Di Jiang, Yuxin Jiang**, Kaili Wang, Zhe Wang, Yifei Pei, Jinglei Wu, Chuanglong He, Xiumei Mo, Hongsheng Wang*，Binary ethosomes-based transdermal patches assisted by metal microneedles significantly improve the bioavailability of carvedilol，Journal of Drug Delivery Science and Technology2022，74，103498
12. Yujie Chen，·Xutao Dong， · Muhammad Shafq， · Gregory Myles， · Norbert Radacsi， · Xiumei Mo*，Recent Advancements on Three‑Dimensional Electrospun Nanofber Scafolds for Tissue Engineering，Advanced Fiber Materials，16， May，2022
13. Liang Song, Xianrui Xie, Cuiting Lv, Atta ur Rehman Khan, Yang Sun, Ruixue Li, Juan Yao, Mohamed EL-Newehy, Hany EL-Hamshary, Yosry Morsi, Xiumei Mo**, Youcheng Yu*，Electrospun biodegradable nanofibers loaded with epigallocatechin gallate for guided bone regeneration，Composites Part B，2022, 238, 109920
14. AbdElAziz A. Nayl* , Ahmed I. Abd-Elhamid, Nasser S. Awwad, Mohamed A. Abdelgawad, Jinglei Wu, Xiumei Mo, Sobhi M. Gomha, Ashraf A. Aly and Stefan Bräse *，Review of the Recent Advances in Electrospun Nanofibers Applications in Water Purification, Polymers 2022, 14, 1594.
15. AbdElAziz A. Nayl 1*, Ahmed I. Abd‐Elhamid, Nasser S. Awwad, Mohamed A. Abdelgawad 4, Jinglei Wu, Xiumei Mo, Sobhi M. Gomha, Ashraf A. Aly and Stefan Bräse*, Recent Progress and Potential Biomedical Applications of Electrospun Nanofibers in Regeneration of Tissues and Organs，Polymers 2022, 14, 1508. //doi.org/10.3390/polym14081508
16. Zhengchao Yuan, Dandan Sheng, Liping Jiang, Muhammad Shafiq∗, Atta ur Rehman Khan , Rashida Hashim, Yujie Chen, Baojie Li, Xianrui Xie, Jun Chen, Yosry Morsi , Xiumei Mo∗, Shiyi Chen∗, Vascular Endothelial Growth Factor-Capturing Aligned Electrospun Polycaprolactone/Gelatin Nanofibers Promote Patellar Ligament Regeneration, Acta Biomaterialia 2022, 140. 233-246
17. C. Chen, J. Zhu, J. Chen, F. Yu, K. Huang, J. Jiang, T. Zhu, ***, X. Mo**, J. Zhao*, A reinforced nanofibrous patch with biomimetic mechanical properties and chondroinductive effect for rotator cuff tissue engineering，Materials Today Chemistry 2022, 23, 100655
18. Wencheng Liang, Qiaohui Lu, Fan Yu, Junyong Zhang, Chuang Xiao, Xiaoming Dou, Yan Zhou, Xiumei Mo, Jun Li * and Meidong Lang *，A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing，Biomaterials Science., 2021, 9, 7124–7133
19. Yujie Chen, Wei Xu, Muhammad Shafiq, Jincheng Tang, Junxiang Hao, Xianrui Xie,Zhengchao Yuan, Xianghao Xiao, Yu Liu*, Xiumei Mo*，Three-dimensional porous gas-foamed electrospun nanofiber scaffold for cartilage regeneration，Journal of Colloid and Interface Science, 2021, 603, 94–109
20. Zhengchao Yuan, Yijiu , ACS Biomaterials Science & Engineering 2021, 7, 3, 904-915
27. Haiyan LI, Mingyue LIU, Xiaoyu WANG, Hongsheng WANG, Xiumei MO and Jinglei WU *, Nanofiber Configuration of Electrospun Scaffolds Dictating Cell Behaviors and Cell-scaffold Interactions, Chem. Res. Chinese Universities, 2021,37(3), 456-463
28. Mingyue Liu, Xiaoyu Wang, Haiyan Li, Changlei Xia, Zhengni Liu, Jiajie Liu, Anlin Yin, Xiangxin Lou, Hongsheng Wang, Xiumei Mo and Jinglei Wu*, Magnesium oxide-incorporated electrospun membranes inhibit bacterial infections and promote the healing process of infected wounds, J. Mater. Chem. B, 2021, 9, 3727–3744
29. Huoyan HONG, Dongdong ZHANG, Si LIN, Feng HAN, Kaili WANG, Di JIANG, Jinglei WU*, Xiumei MO and Hongsheng WANG*, Green Electrospun Silk Fibroin Nanofibers Loaded with Cationic Ethosomes for Transdermal Drug Delivery, Chem. Res. Chinese Universities, //link.springer.com/article/10.1007%2Fs40242-021-1084-8
30. Yan Li†, Juan Wang†, Dejian Qian, Liang Chen, Xiumei Mo, Lei Wang, Yan Wang* and Wenguo Cui*, Electrospun fbrous sponge via short fber for mimicking 3D ECM, Journal of Nanobiotechnology, 2021,19, 131
31. Dongsheng Li, Wendell Q. Sun, Tong Wang, Yonglin Gao, Jinglei Wu, Zeping Xie, Juanjuan Zhao, Chuanglong He, Meifang Zhu, Shumin Zhang, Peng Wang* , Xiumei Mo*，，2020, 110, 110705
67. Jia Liu, Jun Li, Fan Yu, Ya-xin Zhao, Xiu-mei Mo, Jian-feng Pan，In situ forming hydrogel of natural polysaccharides through Schiff base reaction for soft tissue adhesive and hemostasis，International Journal of Biological Macromolecules, 2020, 147, 653-666
68. Jun Li, Fan Yu, Gong Chen, Jia Liu, Xiao-Long Li, Biao Cheng, Xiu-Mei Mo*, Cheng Chen*, and Jian-Feng Pan*, Moist-Retaining, Self-Recoverable, Bioadhesive, and Transparent in Situ Forming Hydrogels To Accelerate Wound Healing，ACS Appl. Mater. Interfaces 2020, 12, 2023-2038
69. Weiming Chen, Yong Xu, Yaqiang Li, Litao Jia, Xiumei Mo*, Gening Jiang*, Guangdong Zhou*, 3D printing electrospinning fiber-reinforced decellularized extracellular matrix for cartilage regeneration, Chemical Engineering Journal, 2020, 382, 122986, If=10.652
70. Linlin Ma, Xiaoyun Wang, Jinglei Wu, Dongdong Zhang, Lin Zhang, Xinran Song, Huoyan Hong, Chuanglong He, Xiumei Mo, Sufang Wu*, Guoyin Kai*, Hongsheng Wang*, Polyethylenimine and sodium cholate-modified ethosomes complex as multidrug carrier for the treatment of melanoma through transdermal delivery，Nanomedicine 2019
71. Dawei Jin, Junfeng Hu, Dekai Xia, A’li Liu, Haizhu Kuang, Jun Du, Xiumei Mo*, Meng Yin*, Evaluation of a simple off-the-shelf bi-layered vascular scaffold based on poly(L-lactide-co-ε-caprolactone) /silk fibroin in vitro and in vivo, International Journal of Nanomedicine 2019:14 4261–4276
72. Tong Wu, Haoxuan Li, Jiajia Xue, Xiumei Mo, and Younan Xia*，Photothermal Welding, Melting, and Patterned Expansion of Nonwoven Mats of Polymer Nanofibers for Biomedical and Printing Applications，Angew. Chem. Int. Ed. 2019, 58, 16416 –16421
73. Tong Wu, Haoxuan Li, Minghao Xie, Song Shen, Wenxia Wang, Ming Zhao, Xiumei Mo, Younan Xia*, Incorporation of gold nanocages into electrospun nanofibers for efficient water evaporation through photothermal heating,Materials Today Energy 2019, 12, 129-135
74. Fei Yu, Runqing Fu, Lu Liu, Xiaoting Wang, Tingting Wu, Wei Shen, Zhipeng Gui, Xiumei Mo*, Bing Fang* and Lunguo Xia*，Leptin-Induced Angiogenesis of EA.Hy926 Endothelial Cells via the Akt and Wnt Signaling Pathways In Vitro and In Vivo，Frontiers in Pharmacology, 2019,10,1275, doi: 10.3389/fphar.2019.01275
75. Atta ur Rehman Khan, Muhammad Nadeem, M. Aqeel Bhutto, Fan Yu, Xianrui Xie, Hany El-Hamshary, Ayman El-Faham, Usama A. Ibrahim and Xiumei Mo*，Physico-Chemical and Biological Evaluation of PLCL/SF Nanofibers Loaded with Oregano Essential Oil，Pharmaceutics 2019, 11, 386; doi:10.3390/pharmaceutics11080386
76. Xianrui Xie, Dongsheng Li, Changming Su, Wei Cong, Xiumei Mo, Guige Hou*, and Chunhua Wang*, Functionalized Biomimetic Composite Nanfibrous Scaffolds with Antibacterial and Hemostatic Efficacy for Facilitating Wound Healing, Journal of Biomedical Nanotechnology, 2019, 15, 1267–1279
77. Wei Zhai, Li-jun Qiu, Xiu-mei Mo, Sheng Wang, Yun-fei Xu, Bo Peng, Min Liu, Jun-hua Huang, Guang-chun Wang, Jun-hua Zheng*, Coaxial electrospinning of P(LLA-CL)/heparin biodegradable polymer nanofibers: potential vascular graft for substitution of femoral artery, J Biomed Mater Res Part B 2019: 107B: 471-478
78. Mingjun Du#, Jianmin Gu#，Juan Wang, Yizheng Xue, Yiwen Ma, Xiumei Mo* and Song Xue*，Silk fibroin/poly(L‑lactic acid‑co‑ε‑caprolactone) electrospun nanofibrous scaffolds exert a protective effect following myocardial infarction，Experimental and Therapeutic Medicine 2019, 17: 3989-3998
79. Weiming Chen, Yong Xu, Yanqun Liu, ZongxinWang, Yaqiang Li, Gening Jiang, Xiumei Mo*, Guangdong Zhou*, Three-dimensional printed electrospun fiber-based scaffold for cartilage regeneration, Materials and Design 2019, 179, 107886， IF=6.286
80. Dawei Jin, Junfeng Hu, Dekai Xia, A’li Liu, Haizhu Kuang, Jun Du, Xiumei Mo*, Meng Yin*, Evaluation of a simple off-the-shelf bi-layered vascular scaffold based on poly(L-lactide-co-ε-caprolactone) /silk fibroin in vitro and in vivo, International Journal of Nanomedicine2019:14 4261–4276
81. Juan Wang, Wei Zheng, Liang Chen, Tonghe Zhu, Wei Shen, Cunyi Fan, Hongjun Wang, and Xiumei Mo*, Enhancement of Schwann Cells Function Using Graphene-OxideModified Nanofiber Scaffolds for Peripheral Nerve Regeneration, ACS Biomater. Sci. Eng. 2019, 5（5）, 2444−2456
82. Kaiqiang Ye, Haizhu Kuang, Zhengwei You, Yosry Morsi and Xiumei Mo*，Electrospun Nanofibers for Tissue Engineering with Drug Loading and Release，Pharmaceutics 2019, 11, 182; doi:10.3390/pharmaceutics11040182
83. Dongdong Zhang, Linpeng Fan, Linlin Ma, Junqiu Liu, Kai Zhou, Xinran Song, Meiqi Sun, Xiumei Mo, Chuanglong He, Yuxin Chen*, and Hongsheng Wang*, Helicobacter pylori Ribosomal Protein-A2 Peptide/Silk Fibroin Nanofibrous Composites as Potential Wound Dressing, J. Biomed. Nanotechnol.2019, 15(3), 507-517
84. Dinghua Liu, Wei Nie, Dejian Li, Weizhong Wang, Lixia Zheng, Jingtian Zhang, Jiulong Zhang, Chen Peng, Xiumei Mo, Chuanglong He*, 3D printed PCL/SrHA scaffold for enhanced bone regeneration, Chemical Engineering Journal 2019, 362, 269–279
85. Xiaojun Zhou, Qianqian Zhang, Liang Chen, Wei Nie, Weizhong Wang, Hongsheng Wang, Xiumei Mo, and Chuanglong He*, Versatile Nanocarrier Based on Functionalized Mesoporous Silica Nanoparticles to Codeliver Osteogenic Gene and Drug for Enhanced Osteodifferentiation, ACS Biomater. Sci. Eng. 2019, 5, 710−723
86. Dong Lei, Yang Yang, Zenghe Liu, Shuo Chen, Benyan Song, Ao Shen, Binqian Yang, Sen Li, Zhize Yuan, Quan Qi, Lijie Sun, Yifan Guo, Han Zuo, Shixing Huang, Qi Yang, Xiumei Mo, Chuanglong He, Bo Zhu, Eric M. Jeffries, Feng-Ling Qing, Xiaofeng Ye,* Qiang Zhao* and Zhengwei You *, A general strategy of 3D printing thermosets for diverse applications, Mater. Horiz., 2019, 6, 394-404
87. Dongsheng Li, Yonglin Gao, Yunzhi Wang, Xiaoping Yang, Chuanglong He, Meifang Zhu, Shumin Zhang and Xiumei Mo*，Evaluation of biocompatibility and immunogenicity of micro/nanofiber materials based on tilapia skin collagen，Journal of Biomaterials Applications, 2019, 33（8）1118–1127
88. XuranGuo, JinjingZhu,HongmeiZhang, ZhengweiYou,Yosory Mosi,Xiumei Mo*, Tonghe Zhu*, Facile preparation of a controlled-release tubular scaffold forblood vesselimplantation, JournalofColloid and InterfaceScience, 2019, 539, 351-360
89. Lijie Sun, Min Wang, Shuo Chen, Binbin Sun, Yifan Guo, Chuanglong He, Xiumei Mo, Bo Zhu, Zhengwei You*, Molecularly engineered metal-based bioactive soft materials – Neuroactive magnesium ion/polymer hybrids，Acta Biomaterialia 2019，85 310–319
90. Juan Wang, Yuan Cheng, Liang Chen, Tonghe Zhu, Kaiqiang Ye, Chao Jia, Hongjun Wang, Meifang Zhu, Cunyi Fan*, Xiumei Mo* , In vitro and in vivo studies of electroactive reduced graphene oxide-modified nanofiber scaffolds for peripheral nerve regeneration，Acta Biomaterialia 2019, 84, 98–113
91. Kaiqiang Ye, Dinghua Liu, Haizhu Kuang, Jiangyu Cai, Weiming Chen, Binbin Sun, Lunguo Xia, Bing Fang, Yosry Morsi, Xiumei Mo*，Three-dimensional electrospun nanofibrous scaffolds displaying bone morphogenetic protein-2-derived peptides for the promotion of osteogenic differentiation of stem cells and bone regeneration，Journal of Colloid and Interface Science 2019, 534, 625–636, IF=7.489，
92. Binbin Sun, Zifei Zhou, Dawei Li, Tong Wu, Hao Zheng, Junjian Liu, Gangyang Wang, Yinxian Yu* , Xiumei Mo*，Polypyrrole-coated poly(l-lactic acid-co-ε-caprolactone)/silk fibroin nanofibrous nerve guidance conduit induced nerve regeneration in rat, Materials Science & Engineering C , 2019, 94 , 190–199
93. Haizhu Kuang, Shuofei Yang, Yao Wang, Yuting He, Kaiqiang Ye, Junfeng Hu, Wei Shen, Yosry Morsi, Shuyang Lu∗, and Xiumei Mo∗, Electrospun Bilayer Composite Vascular Graft with an Inner Layer Modified by Polyethylene Glycol and Haparin to Regenerate the Blood Vessel, J. Biomed. Nanotechnol. 2019, 15（1），77–84
其他信息
2. 中国生物材料学会心血管材料分会委员
3. 中国生物材料学会海洋生物材料分会理事
4. 中国生物医学工程学会生物材料分会理事
5. 中国复合材料学会超细纤维复合材料分会副主任委员
6. 中国复合材料学生物医用复合材料分会委员
7. 上海市生物医学工程学会理事
8. 上海市生物医学工程学会生物材料专业委员会委员
9. 中国研究型医院学会运动医学专业委员会委员
10. 中国医学装备协会组织再生分会常务委员
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